Avatars Help Stroke Patients Improve Motor Function

©Nate Jensen
 
I am hooked up to a 16-channel brain machine interface with 12 channels of EEG on my head and ears and four channels of electromyography (EMG) on my arms. An Oculus Rift occludes my vision.
 
Two inertial measurement units (IMU) are stuck to my wrists and forearms, tracking the orientation of my arms, while the EMG monitors my electrical impulses and peripheral nerve activity.
 
Dr. Sook-Lei Liew, Director of USC’s Neural Plasticity and Neurorehabilitation Laboratory, and Julia Anglin, Research Lab Supervisor and Technician, wait to record my baseline activity and observe a monitor with a representation of my real arm and a virtual limb. I see the same image from inside the Rift.
 
“Ready?” asks Dr. Liew. “Don’t move—or think.”
 
I stay still, close my eyes, and let my mind go blank. Anglin records my baseline activity, allowing the brain-machine interface to take signals from the EEG and EMG, alongside the IMU, and use that data to inform an algorithm that drives the virtual avatar hand.
 
“Now just think about moving your arm to the avatar’s position,” says Dr. Liew.
 
I don’t move a muscle, but think about movement while looking at the two arms on the screen. Suddenly, my virtual arm moves toward the avatar appendage inside the VR world.

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Something happened just because I thought about it! I’ve read tons of data on how this works, even seen other people do it, especially inside gaming environments, but it’s something else to experience it for yourself.
 
“Very weird isn’t it?” says David Karchem, one of Dr. Liew’s trial patients. Karchem suffered a stroke while driving his car eight years ago, and has shown remarkable recovery using her system.
 
“My stroke came out of the blue and it was terrifying, because I suddenly couldn’t function. I managed to get my car through an intersection and call the paramedics. I don’t know how,” Karchem says.
 
He gets around with a walking stick today, and has relatively normal function on the right side of his body. However, his left side is clearly damaged from the stroke. While talking, he unwraps surgical bandages and a splint from his left hand, crooked into his chest, to show Dr. Liew the progress since his last VR session.
 
As a former software engineer, Karchem isn’t fazed by using advanced technology to aid the clinical process. “I quickly learned, in fact, that the more intellectual and physical stimulation you get, the faster you can recover, as the brain starts to fire. I’m something of a lab rat now and I love it,” he says.
 
REINVENT Yourself
Karchem is participating in Dr. Liew’s REINVENT (Rehabilitation Environment using the Integration of Neuromuscular-based Virtual Enhancements for Neural Training) project, funded by the American Heart Association, under a National Innovative Research Grant. It’s designed to help patients who have suffered strokes reconnect their brains to their bodies.

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“My PhD in Occupational Science, with a concentration in Cognitive Neuroscience, focused on how experience changes brain networks,” explains Dr. Liew. “I continued this work as a Postdoctoral Fellow at the National Institute of Neurological Disorders and Stroke at the National Institutes of Health, before joining USC, in my current role, in 2015.
 
“Our main goal here is to enhance neural plasticity or neural recovery in individuals using noninvasive brain stimulation, brain-computer interfaces and novel learning paradigms to improve patients’ quality of life and engagement in meaningful activities,” she says.
 
Here’s the science bit: the human putative mirror neuron system (MNS) is a key motor network in the brain that is active both when you perform an action, like moving your arm, and when you simply watch someone else—like a virtual avatar—perform that same action. Dr. Liew hypothesizes that, for stroke patients who can’t move their arm, simply watching a virtual avatar that moves in response to their brain commands will activate the MNS and retrain damaged or neighboring motor regions of the brain to take over the role of motor performance. This should lead to improved motor function.

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Source: PC Mag

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